[6-(2-Nitrophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]methanol
[6-(2-nitrophenyl)imidazo[2,1-b]thiazol-3-yl]methanol
CAS: 925437-85-0
Molecular Formula: C12H9N3O3S
[6-(2-Nitrophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]methanol - Names and Identifiers
[6-(2-Nitrophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]methanol - Physico-chemical Properties
| Molecular Formula | C12H9N3O3S |
| Molar Mass | 275.28 |
| Density | 1.59±0.1 g/cm3(Predicted) |
| pKa | 14.27±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.765 |
[6-(2-Nitrophenyl)imidazo[2,1-b][1,3]thiazol-3-yl]methanol - Introduction
[6-(2-nitrophenyl)imidazo[2,1-b]thiazol-3-yl]methanol is an organic compound whose molecular formula is C13H9N3O3S. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Yellow solid
-Melting point: about 150-152°C
-Solubility: Soluble in organic solvents, such as dimethyl sulfoxide and dichloromethane, insoluble in water.
-Stability: Stable under certain conditions.
Use:
-Drug: It has certain biological activity and can be used as an intermediate for anti-inflammatory drugs and anti-tumor drugs.
-Research: As reagents and intermediates in organic synthesis.
Method:
[6-(2-nitrophenyl)imidazo[2,1-b]thiazol-3-yl]methanol are generally prepared by chemical synthesis. A common method of preparation is:
1. First, 2-nitrobenzaldehyde and methyl thiocyanate are reacted at high temperature in the presence of sodium hydroxide to obtain aldehyde intermediates.
2. Subsequently, the aldehyde intermediate is reacted with sodium sulfite in ethanol to generate an imidazothiazole ring structure.
3. Finally, the imidazothiazole ring structure was reacted with NaBH4 to obtain the final product [6-(2-nitrophenyl)imidazo[2,1-b]thiazol-3-yl]methanol.
Safety Information:
-There are no detailed safety studies and evaluation reports for this compound, so complete safety information is lacking.
-When handling the compound, care should be taken to follow the laboratory's safe operating procedures, including wearing appropriate personal protective equipment, such as gloves, goggles, and laboratory coats to prevent skin contact or inhalation.
-Do not expose this compound to fire or high temperature to avoid the risk of fire or explosion.
-Please store and handle the compound properly to avoid environmental pollution and personal safety.
Nature:
-Appearance: Yellow solid
-Melting point: about 150-152°C
-Solubility: Soluble in organic solvents, such as dimethyl sulfoxide and dichloromethane, insoluble in water.
-Stability: Stable under certain conditions.
Use:
-Drug: It has certain biological activity and can be used as an intermediate for anti-inflammatory drugs and anti-tumor drugs.
-Research: As reagents and intermediates in organic synthesis.
Method:
[6-(2-nitrophenyl)imidazo[2,1-b]thiazol-3-yl]methanol are generally prepared by chemical synthesis. A common method of preparation is:
1. First, 2-nitrobenzaldehyde and methyl thiocyanate are reacted at high temperature in the presence of sodium hydroxide to obtain aldehyde intermediates.
2. Subsequently, the aldehyde intermediate is reacted with sodium sulfite in ethanol to generate an imidazothiazole ring structure.
3. Finally, the imidazothiazole ring structure was reacted with NaBH4 to obtain the final product [6-(2-nitrophenyl)imidazo[2,1-b]thiazol-3-yl]methanol.
Safety Information:
-There are no detailed safety studies and evaluation reports for this compound, so complete safety information is lacking.
-When handling the compound, care should be taken to follow the laboratory's safe operating procedures, including wearing appropriate personal protective equipment, such as gloves, goggles, and laboratory coats to prevent skin contact or inhalation.
-Do not expose this compound to fire or high temperature to avoid the risk of fire or explosion.
-Please store and handle the compound properly to avoid environmental pollution and personal safety.
Last Update：2024-04-09 21:01:54
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Product Name: 3-HYDROXYMETHYL-6-(2-NITROPHENYL)IMIDAZO[2,1-B]THIAZOLE Visit Supplier Webpage Request for quotation
CAS: 925437-85-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 925437-85-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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